estimated 9 million people aged 12 and older used prescription drugs for non-medical
reasons in 1999; more than a quarter of that number reported using prescription
drugs non-medically for the first time in the previous year.
What is Ativan?
Ativan is the brand name for Lorazepam, an anti-anxiety agent. Ativan is a benzodiazepine
and mild tranquilizer, sedative, and central nervous system (CNS) depressant.
Ativan is manufactured in pill form as well as liquid form for injection.
How is Ativan used?
Ativan tablets are a nearly white powder and are almost insoluble in water. Each
Ativan tablet intended for oral use contains .5mg, 1mg, or 2mg of lorazepam. In
liquid form Ativan is intended for intramuscular or intravenous use. Each ml or
Ativan injection contains either 2.0 or 4.0 mg of lorazepam, 0.18 ml polyethylene
glycol 400 in propylene glycol with 2.0% benzyl alcohol as preservative.
When are the effects of Ativan typically felt?
The effects of Ativan are usually felt one to five minutes after receiving it
intravenously, 15 to 30 minutes after muscular injection, or 1 to 6 hours after
Is Ativan considered addictive?
Yes, Ativan is very addictive and can cause psychological and physical dependence.
What are the side effects of Ativan?
There are many side effects that come with the use and abuse of Ativan, they included
but are not limited to:
dizziness, sleepiness, unsteadiness, weakness, amnesia, insomnia, agitation, disorientation,
depression, headache, visual problems, nausea, abdominal discomfort, drowsiness,
blurred vision, tachycardia, weakness, disinhibition (where they act inappropriately
grandiose or out-of-control), anterograde amnesia (decreased or lack of recall
of events during period of drug action) has been reported after administration
of Ativan and appears to be dose-related, injectable Ativan results in an increased
incidence of sedation, hallucination, and irrational behavior, some patients on
Ativan have developed leukopenia, both elevation and lowering of blood sugar levels
have been reported.
Memory functioning is markedly and measurably impaired,
especially the ability to store acquired knowledge into long-term memory. This
memory impairment is highly relevant to students. The risk of acute amnesia is
more pronounced with short-acting drugs. Ativan (lorazepam), Halcion (triazolam),
Xanax (alprazolam) and Rohypnol (flunitrazepam) are especially likely to induce
such memory impairment.
What are the symptoms of withdrawal?
Withdrawal symptoms, similar in character to those noted with barbiturates and
alcohol (convulsions, tremor, abdominal and muscle cramps, vomiting, and sweating),
have occurred following abrupt discontinuance of Ativan. The more severe withdrawal
symptoms have usually been limited to those patients who received excessive doses
over an extended period of time.
What are the symptoms of Ativan overdose?
The symptoms of Ativan overdose are degrees of central nervous system depression
ranging from drowsiness to coma. In mild cases, symptoms include drowsiness, mental
confusion, and lethargy. In more serious cases, and especially when other drugs
or alcohol were ingested, symptoms may include ataxia, hypotonia, hypotension,
hypnotic state, stage one (1) to three (3) coma, and very rarely, death.
What drug interactions occur with Ativan?
Drugs or substances that may interact with Ativan include:
Clozaril (clozapine) - when taken with Ativan can increase side effects such as
sedation and loss of coordination
2. Heparin, Macrolide antibiotics, Depakene
(valproic acid), and Benemid (probenecid) - when taken with Ativan can increase
3. Birth control pills, caffeine/amphetamines/other stimulants,
and Theo-Dur (theophylline) - these drugs can reduce Ativan's effects
Lithium - when taken with Ativan can lower body temperature
5. Perocet (oxycodone)
and other central nervous system (CNS) depressants - can cause a slower rate of
breathing when taken with Ativan
6. Dilantin (pheytoin) - can cause Dilatin
or Ativan blood levels to change
7. Narcotics, marijuana, tobacco smoking
- can increase sedation
8. Sedatives, sleeping pills, other benzodiazepines
- combination with Ativan could cause death
9. Alcohol - when taken with
Ativan can lower breathing rate and blood pressure resulting in unconsciousness
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